Treatment

Treating Kidney Stones: Medicines

Choose a preferred language


In some cases, your doctor may prescribe medicines to dissolve or prevent kidney stones. Or medicine may be prescribed to stop an infection. Once the infection is controlled, the stone can be removed.

Man taking a pill with a glass of water.


Medicines

Be certain your doctor knows your full health history before you start kidney stone medicines. Some kidney stone medicines have serious side effects. The longer you take the medicine and the higher the dose, the more likely the side effects will occur. Let your doctor know right away if you have any side effects.

For uric acid or cystine stones, your doctor may prescribe medicines. You'll take these for your lifetime. Medicines can't dissolve calcium oxalate stones. But they often help prevent them. If you have an infection stone, also called a struvite stone, your doctor may prescribe antibiotics. You may take these before and after your stone is removed.

Uric acid stones are caused by too much uric acid in your urine. This can be worsened by a high-meat diet. Allopurinol reduces uric acid. The stone can be dissolved with bicarbonate, potassium citrate, or a similar drug.

Cystine stones are caused by too much cystine (an amino acid) in your urine. This condition is uncommon and inherited. Penicillamine or tiopronin reduces cystine. Bicarbonate, potassium citrate, or a similar drug dissolves cystine stones.

Calcium stones are caused by a number of different things. If you have too much calcium in your urine, your doctor may prescribe diuretics. If your urine has too much oxalate or if your stones are from too little citrate, your doctor may give you a different medicine.

Infection stones are caused by chronic kidney or bladder infections that change the chemical balance of your urine. Antibiotics control the infection. And they may slow the stone's growth. Then, your stone is removed. Stone infections are caused by bacteria that make an enzyme called urease. Your doctor may use a medicine to block this enzyme. They may also prescribe medicines to relax the ureters. This will allow the stone to pass through more quickly.

Online Medical Reviewer: Marianne Fraser MSN RN

Online Medical Reviewer: Raymond Kent Turley BSN MSN RN

Online Medical Reviewer: Walead Latif MD

Date Last Reviewed: 09/01/2025

© 2000-2026 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.

Your family’s health is our priority.

From routine checkups to specialized pediatric care, our family of doctors is here for yours.

Find a Doctor
Related Articles
Read article
Urology
Preventing Kidney Stones

If you've had a kidney stone, you may worry that you'll have another. Removing or passing your stone doesn't prevent future stones. But with your health care provider's help you can reduce your risk of forming new stones.

Read article
Urology
Treating Kidney Stones: Expectant Therapy

Most kidney stones are about the size of a grape seed. Stones of this size are small enough to pass naturally. Once it is passed, a stone can be analyzed. This wait-and-see approach is called expectant therapy.

Read article
Urology
Kidney Stone, Passed

The sharp, cramping pain and nausea/vomiting you had was due to the stone moving through the ureter (the narrow tube joining the kidney to the bladder). Once the stone reaches your bladder, the pain stops. Pain may begin again as the stone passes through the bladder and out through the urethra.

Read article
Urology
Kidney Stones: Are You at Risk?

Assess your risk factors by answering these questions.